Thyroid is the major gland in the centre of your neck that is responsible for your metabolism. Hence, you can say that the optimal functioning of this gland is more or less necessary for the smooth functioning of your body.
Around 25 million Americans suffer from the thyroid problem where half of them do not even know or feel their suffering. The main issue related to thyroid is the problem of under-active thyroid, i.e. hypothyroidism.
Working of thyroid gland:
The hypothalamus, pituitary gland and the thyroid gland are the major functionaries for the production of thyroid hormones. Hypothalamic thyrotropin-releasing hormone (TRH) causes pituitary thyrotropin (TSH) synthesis and secretion.
Furthermore, TSH affects the production and secretion of T4 (inactive form of hormone) and T3 (active) from the gland. The function of T4 is to signal TRH and TSH to stop the production of thyroid hormone after a certain amount. As the production of T4 is more, some of them get converted into T3. Also, some of the T3 get converted into either Free T3 (FT3) or Reverse T3 (RT3). Free T3 is the most important hormone here as it has the ability to raise our metabolism by attaching to a receptor, keeping us warm, our mind healthy, and our bowel movement intact.
The most common form of hypothyroidism is Hashimoto's thyroiditis, which is an auto-immune disease.
The under diagnosed cases of hypothyroidism in USA:
The problem shoots up when most of the doctor in USA go after TSH and T4 test results and neglect FT3, RT3 or other thyroid related hormones. They ignore the symptoms of their patients, and just look out for the generic lab references.
Lab tests for Thyroid problems:
- Free T4
- Free T3
- Reverse T3
- Thyroid Peroxidase Antibodies (TPOAb)
- Thyroglobulin Antibodies (TgAb)
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